Does Circadian Rhythm Disorder Always Harm Organisms? Positive Effects of Circadian Rhythm Disorder in Lates calcarifer

Circadian Rhythm and Bipolar Disorder Impact of Circadian Rhythm Disturbances in Bipolar Disorder

Circadian Rhythm Sleep Disorder: Irregular Sleep Wake Rhythm Type.

Irregular Sleep Wake Rhythm Disorder (ISWRD) is characterized by the relative absence of a circadian pattern in an individual's sleep-wake cycle. Significant changes in circadian regulation occur with aging and with neurodegenerative diseases, such as Alzheimer's disease prevalent in older adults, which are likely to contribute to the prevalence of ISWRD seen in these populations, although ISWR...

Circadian rhythm disorder in a rare disease: Smith-Magenis syndrome.

Smith-Magenis syndrome (SMS) is a clinically recognizable contiguous gene syndrome, caused by interstitial deletion of chromosome 17p11.2. The SMS phenotype include distinctive facial features, developmental delay and neurobehavioral abnormalities. The patients present major sleep disturbances ascribed to a phase shift of their circadian rhythm of melatonin with a paradoxical diurnal secretion ...

Familial Circadian Rhythm Disorder in the Diurnal Primate, Macaca mulatta

In view of the inverse temporal relationship of central clock activity to physiological or behavioral outputs in diurnal and nocturnal species, understanding the mechanisms and physiological consequences of circadian disorders in humans would benefit from studies in a diurnal animal model, phylogenetically close to humans. Here we report the discovery of the first intrinsic circadian disorder i...

A circadian rhythm sleep disorder: melatonin resets the biological clock.

Circadian rhythm sleep disorders are poorly understood and often misdiagnosed. They are all related to the timing of sleep within the 24-hour day. This paper describes a patient with a long history of sleep disturbance whom we diagnosed as having delayed sleep phase syndrome by history and measurement of urinary melatonin metabolite excretion. Literature on the characteristics, diagnosis and ma...